While both types can help treat ADHD, people also use immediate-release Adderall to treat narcolepsy , which is a sleep disorder. The following table lists the available dosages for Adderall and Adderall XR in milligrams mg. If someone has difficulty swallowing Adderall XR, they can open the capsule and sprinkle the beads on applesauce. A doctor may prescribe immediate-release Adderall to a preschool-aged child starting at a dose of 2.
For this dose, people can split a 5 mg tablet in half. The starting dose of Adderall XR for children and adolescents between 6 and 17 years old is 10 mg once a day in the morning.
Doctors will start adults at a higher dose of 20 mg once daily. The active ingredient in Vyvanse is lisdexamfetamine. Lisdexamfetamine is an inactive drug that the body breaks down into dextroamphetamine in the bloodstream. Dextroamphetamine is one of the same active ingredients that Adderall contains. Vyvanse is available in a capsule or in a chewable form. If someone has difficulty swallowing, they can open the capsule and dissolve the contents in water.
The following table lists the dosages of both forms of Vyvanse. The starting dose of Vyvanse to treat ADHD in people 6 years and older is 30 mg once daily in the morning. The doctor can increase the dose by 10 to 20 mg every week until the medication achieves the desired effect.
Some adults take Vyvanse for moderate to severe binge eating disorder. Doctors can prescribe immediate-release Adderall in people over 6 years old to treat narcolepsy. Both Vyvanse and Adderall are stimulants of the central nervous system and are among the first choices of medications that doctors will prescribe for treating ADHD. The drugs differ in their length of action :.
Sometimes, people who take Adderall XR need a short-acting amphetamine at the end of the effect to extend the control of their symptoms. Since the body converts Vyvanse into dextroamphetamine, both Vyvanse and Adderall have the same drug interactions. As with other stimulants, people should avoid using certain types of antidepressants — namely monoamine oxidase inhibitors — with Vyvanse, Adderall, or Adderall XR.
A person must stop taking these drugs 14 days before starting Vyvanse or Adderall XR. For binge eating disorder , doctors can prescribe Vyvanse because researchers have demonstrated its efficacy through clinical studies. One of the most significant differences between Vyvanse and Adderall is that Vyvanse remains inactive until the body breaks it down in the bloodstream.
The effect of Vyvanse can last longer than that of Adderall XR. Vyvanse provides a maximum of 12 hours of symptom control. Lisdexamfetamine is converted to dextroamphetamine and l-lysine primarily in the blood. This occurs due to the hydrolytic activity of red blood cells. The conversion of lisdexamfetamine in the blood produces dextroamphetamine, a non-catecholamine sympathomimetic amine with central nervous system CNS stimulant activity.
Amphetamines block the reuptake of catecholamines norepinephrine and dopamine into the presynaptic neuron and increase the release of these monoamines into the extraneuronal space. The parent drug, lisdexamfetamine, does not bind to the sites responsible for the reuptake of norepinephrine and dopamine in vitro. Learn more about Vyvanse and the efficacy and safety data by clicking on the links below.
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Please see our Terms of Use for more information. While Takeda makes reasonable efforts to include accurate, up-to-date information on this site, Takeda makes no warranties or representations as to its accuracy. It is available in one formula that was approved by the FDA in for people 6 years and older.
There is little comparative research to suggest that one is better than the other. The two medications do differ in terms of how long they last. This can be a deciding factor for many people and can impact how effective the medication is for controlling symptoms. Some people taking Adderall XR may find that they need to take other medications to help control their symptoms.
As Vyvanse and Adderall are both amphetamine-type stimulant medications, the side effects of each drug are similar and include:. More serious but rarer side effects include increased heart rate, high blood pressure, shortness of breath, hallucinations, and paranoia.
If you experience these or any other side effects, contact a doctor as soon as possible. There are some additional side effects that need to be considered. Men might experience erectile dysfunction ED when taking an amphetamine. Although you might feel embarrassed to talk about this with your doctor, they will be able to work with you to help resolve this issue. People with certain conditions should not take Vyvanse or Adderall.
For example, you should not take either of these medications if you have:. Adderall and Vyvanse could be unsafe during pregnancy, and they are not recommended while breastfeeding. If you are pregnant, planning to become pregnant, or breastfeeding, talk with your doctor. Since both medications are amphetamines that can be habit-forming, you should also not use them if you have a history of substance abuse. There is also a risk of drug interactions that can occur if you combine Adderall or Vyvanse with another substance.
Medications that you should avoid while taking these ADHD medications include:. Other things that can interact with and affect the actions of Vyvanse and Adderall include alcohol, caffeine, and foods or beverages containing ascorbic acid. Remember to inform your prescribing doctor about any other prescriptions, over-the-counter medications, and natural supplements you might be taking.
While Vyvanse and Adderall share a number of similarities, there are some important differences between the two medications. These differences can play a role in determining which medication is right for you. Perhaps the biggest distinction between Adderall and Vyvanse is that Vyvanse is a prodrug.
The effects of Adderall start to work within 30 minutes. In contrast, Vyvanse takes approximately one to two hours to take effect. Vyvanse is often described as "smoother" than Adderall. One of the reasons for this is that—because it has a slower absorption rate—there is not a "kick" or "jolt" to the system when the medication starts to work. In addition, there is less medication rebound when Vyvanse starts to wear off.
Since Adderall is available in both intermediate and extended versions, it allows for great flexibility in how it can be taken.
For example, a person might be prescribed Adderall XR to take daily and have Adderall IR to take when a more immediate effect is needed or when it is beneficial to have the medication wear off before bedtime. Vyvanse and Adderall are Schedule II drugs, which means there is a potential for abuse and dependency. Both are approved to take orally. Since Vyvanse needs to be converted in the body, it can't be inhaled or injected as a way to become high, so it is less likely to be misused than Adderall and other stimulant medications.
Always store your medications safely and away from other people. Adderall IR is available in tablets ranging from 5 to 30 milligrams mg. Adderall XR is available in six different doses ranging from 5 to 30 mg. Vyvanse is available in capsules and chewable tablets of several strengths in doses from 10 to 70 mg.
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